Abstract Fibroblasts derived from the progeroid Werner syndrome show reduced replicative lifespan and a "stressed" morphology, both alleviated using the MAP kinase inhibitor SB203580.However, interpretation of these data is problematical because although SB203580 has the stress-activated kinases p38 and JNK1/2 as its preferred targets, it does show
The article deals with effects of achievements and consequences of the fourth industrial revolution.The author shows history of agrarian and industrial revolutions and demonstrates specific features of the 4th industrial revolution in comparison with the previous ones, reveals preconditions of its arising and scales of the revolution reforms and di
Background: Anxiety and depression are two important contributors to the global burden of disease.Both conditions are frequently found as comorbidity among patients with substance use disorder and play a major role in its prognosis and relapse.If ignored such psychiatric illness by a mental health professional, can create a gap in the overall treat
Magelang memiliki tingkat kemacetan yang cukup padat pada beberapa ruas jalan terutama yang menuju pusat kota, salah satunya pada simpang Armada Town Square Mall yang kian hari semakin padat.Oleh karena itu, artikel ini menyajikan analisis pemborosan bahan bakar akibat kemacetan dengan menggunakan citra google map.Dalam penelitian ini metode yang d
Wooden Blocks Loop closure detection is an important component of the Simultaneous Localization and Mapping (SLAM) algorithm, which is utilized in environmental sensing.It helps to reduce drift errors during long-term operation, improving the accuracy and robustness of localization.Such improvements are sorely needed, as conventional visual-based l